For health care professionals only

The information contained on this site is intended for use only by health care professionals in the United States. Countries outside of the United States may have different regulatory requirements or medical practices than the United States. Therefore, this information may not be appropriate for use outside of the United States.

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You don't have to feel alone living with inhibitors.
How Does NovoSeven® RT Work?

What is NovoSeven® RT?


NovoSeven® RT is the only recombinant Recombinant
Genetically engineered DNA. Made without human blood or plasma. Factor VII (FVII) Factor VII (seven)
One of the 13 clotting factor proteins that help form blood clots. product available for the treatment of bleeding episodes and prevention of surgical bleeding in patients with hemophilia A Hemophilia A
A bleeding disorder caused by lack of Factor VIII. It is sometimes called classic or standard hemophilia. or B Hemophilia B
A bleeding disorder caused by lack of Factor IX. with inhibitors Inhibitor
A substance made by the body that attacks factor so it cannot work as well. For example, a Factor VIII inhibitor would keep Factor VIII from working with other factors and platelets to stop bleeding. to FVIII or FIX, patients with acquired hemophilia Acquired hemophilia
A form of hemophilia in which the body starts producing antibodies that fight its own blood-clotting proteins. , and patients with FVII deficiency Factor VII (seven) deficiency
A rare bleeding disorder in which the blood has low levels of Factor VII. Factor VII is important in the blood-clotting process because it binds to blood cells near the location of an injury and to activated platelets, setting the clotting process in motion..


How does NovoSeven® RT work?

There are 13 factors Factor
A protein in the blood that helps form blood clots. in the clotting Clotting
The process of forming into a clot or clots. process. Clotting happens when each factor works together in the right order. The clotting process can be slowed or stopped if one factor is blocked or missing. In order for a stable clot to form, the deficient Deficiency
A lack or shortage of something. factor in the blood-clotting process must be replaced or bypassed.

NovoSeven® RT is called a bypassing agent because it skips the need for Factor VIII or IX in people with inhibitors, instead activating Factor X directly. For people with FVII deficiency, NovoSeven® RT is used to replace the missing factor, so the clotting process can continue.

NovoSeven® RT targets the site of injury, bypasses the inhibitor, and stops bleeds fast