NovoSeven® RT (Coagulation Factor VIIa [Recombinant]) is the only bypassing agent FDA approved for acquired hemophilia
What is acquired hemophilia?
A form of hemophilia in which the body starts producing antibodies that fight its own blood-clotting proteins. is a rare and dangerous blood disorder. Each year, it occurs in only 1 to 1.5 per 1 million people. Acquired hemophilia is associated with a wide range of conditions. With acquired hemophilia:
Something that happens on its own, for what seems like no reason. For example, spontaneous bleeding does not appear to have a specific cause., uncontrolled bleeding Bleeding
In hemophilia, a collection of blood in an area, such as a muscle or joint. can occur
- Men and women with no personal or family history of the disease are affected
Symptoms and diagnosis of acquired hemophilia
Acquired hemophilia is hard to detect. The most common symptoms are:
- Bleeding into the skin
- Bleeding into soft tissues
- Internal bleeding
Bleeding inside the body, in tissues or organs.
- Excessive bleeding following surgery
- Excessive bleeding after childbirth
Acquired hemophilia is diagnosed with laboratory tests that measure clotting time
The time required for blood to clot. of blood and factor VIII (8) Factor VIII (8)
One of the 13 clotting-factor proteins that helps form blood clots. levels.