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NovoSeven® RT (Coagulation Factor VIIa [Recombinant]) is effective at controlling bleeds in people with Glanzmann’s thrombasthenia (GT)
who have a decreased or absent response to platelet transfusions

What is GT?

There are proteins on the platelets that help your blood clot properly. One of these proteins is called glycoprotein. One glycoprotein called 2B-3A helps platelets connect to each other by binding to fibrinogen strands, forming bridges between platelets. Those platelets stick together to form a “plug” that stops a bleed.

Someone with GT has specific defective glycoprotein. This means the platelets cannot form a plug to stop a bleed.

Who gets GT?

GT is a rare genetic disorder that affects about 1 in 1 million people. It is inherited from both parents and can occur in both men and women.

Signs of GT

Those with GT mainly have skin and mucous membrane types of bleeding. The most common signs of GT include:

  • Easy bruising
  • Bleeding from the nose or gums
  • Heavy menstruation (in women)
Other signs and symptoms include:
  • Excessive bleeding after trauma or surgery
  • Excessive bleeding after dental extractions
  • Red- or black-colored stools
  • Vomit that is black and syrupy or bright red
  • Blood in the urine
  • Painful swelling or warmth around a joint may rarely occur

GT is a serious condition and bleeding can be unpredictable. A healthcare provider should always be consulted before treatment begins.

Indications and Usage

NovoSeven® RT (Coagulation Factor VIIa [Recombinant]) is used for:

Important Safety Information


  • Serious blood clots that form in veins and arteries with the use of NovoSeven® RT have been reported.
  • Your healthcare provider should discuss the risks and explain the signs and symptoms of blood clots to you. Some signs of a blood clot may include pain, swelling, warmth, redness, or a lump in your legs or arms, chest pain, shortness of breath, or sudden severe headache and/or loss of consciousness or function.
  • Your healthcare provider should monitor you for blood clots during treatment with NovoSeven® RT.

Warnings and Precautions

Side Effects

Use with Other Drugs

Please click here for NovoSeven® RT Prescribing Information and Instructions for Use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit,
or call 1-800-FDA-1088.

NovoSeven® RT is a prescription medicine. Novo Nordisk provides patient assistance for those who qualify. Please call
1-877-NOVO-777 (1-877-668-6777) to learn more about Novo Nordisk assistance programs.