NovoSeven® RT (Coagulation Factor VIIa [Recombinant]) does not raise inhibitor titers*
Concentration or strength of a substance; measures the strength of an inhibitor in a person’s blood. measures the strength of an inhibitor Inhibitor
A substance made by the body that attacks factor so it cannot work as well. For example, a Factor VIII (8) inhibitor would keep Factor VIII from working with other factors and platelets to stop bleeding. . The higher the titer in the blood, the stronger the inhibitor. With NovoSeven® RT, you do not have to worry about raising your titer.
- NovoSeven® RT was associated with decreases in inhibitor titers
when used as the only factor
A protein in the blood that helps form blood clots. treatment in a study
People with inhibitors want to keep their titers low. However,
Factor VIII (8)
One of the 13 clotting-factor proteins that helps form blood clots. and factor IX (9) Factor IX (9)
One of the 13 clotting-factor proteins that helps form blood clots. can raise titers.
No risk of increased titers with NovoSeven® RT
- NovoSeven® RT is the only
A product that treats a bleed without the need for factor VIII (8) or Factor IX (9). that does not contain any factor VIII or IX, so there is no risk of increased titers with treatment
*Inhibitors to factor VIII or IX.