There are proteins on the platelets that help your blood clot properly. One type of these proteins is a glycoprotein called IIb/IIIa, which helps platelets connect to each other. Those platelets stick together to form a "plug" that stops a bleed. Someone with GT has specific defective glycoprotein IIb/IIIa. This means the platelets cannot form a plug to stop a bleed.
An effective therapy option for you.
NovoSeven® RT is the only recombinant treatment indicated for Glanzmann's thrombasthenia (GT) when platelets don't work.
What is GT?
Who gets GT?
GT is a rare genetic disorder that affects about 1 in 1 million people. It is inherited from both parents and can occur in both men and women.
What are the signs of GT?
Those with GT mainly have skin and mucous membrane types of bleeding. The most common signs of GT include:
- Easy bruising
- Bleeding from the nose or gums
- Heavy menstruation
Other signs and symptoms include:
- Excessive bleeding after trauma or surgery
- Excessive bleeding after dental extractions
What are some treatments for GT?
One treatment option for GT is platelet transfusion; some patients who receive platelet transfusions may develop antibodies and become resistant. You may be able to use a bypassing agent to control your bleeds if platelets do not work for you.
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