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An effective therapy option for you.

NovoSeven® RT is the only recombinant treatment indicated for Glanzmann's thrombasthenia (GT) with refractoriness to platelets.

Controls bleeds, wherever and whenever they happen.

Rely on NovoSeven® RT—it is proven effective to treat GT at home. Clinical trials show it controls bleeds in a majority of GT-related bleeds, and in surgical procedures.

Bleed control seen in clinical trialsa

Real-world efficacy in children (post-clinical trials).

 

  • 94% bleed control in patients 0 to 12 years
  • 100% bleed control in patients >12 to 16 years


aEffectiveness seen in a prospective, observational, multinational study (from an analysis of published cases and people who took part in trials and registries).
bNovoSeven® RT only and NovoSeven® RT with platelets and/or antifibrinolytics.

Goes where you go.

NovoSeven® RT is portable and travel ready, with compact packaging that’s easy to pack in a carry-on or backpack. And because it’s room temperature stable up to 77°F, there's no need to refrigerate.c  

cNovoSeven® RT should be stored between 36°F and 77°F.
For complete storage information, please see Prescribing Information.

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Quick to mix.d

NovoSeven® RT with MixPro® makes mixing a dose as easy as attach, twist, and mix. The prefilled syringe saves time—there are no extra steps to fill a syringe with diluent.

After mixing, NovoSeven® RT may be stored at room temperature in the vial for up to 3 hours—so you can mix a dose, then take it along to infuse later.

dCompared with mixing using histidine vials.

Fast to infuse.

NovoSeven® RT provides low infusion volume, so infusing takes 2 to 5 minutes.e NovoSeven® RT is given as an intravenous (IV) bolus injection.

eAdminister as a slow bolus injection over 2 to 5 minutes, depending on the dose administered.

Safety supported by clinical experience.

NovoSeven® RT is a recombinant product, meaning it is made without human blood or plasma. This minimizes the possibility of viral contamination. NovoSeven® RT is the only recombinant therapy indicated for GT.f And its safety is supported by real-world evidence, with a <0.2% rate of unexpected blood clots reported. 

Serious blood clots that form in veins and arteries with the use of NovoSeven® RT have been reported.

fIn patients with refractoriness to platelet transfusions, with or without antibodies to platelets.

Icon: Microscrope

What if I need surgery or a procedure?

We understand that you have concerns about controlling bleeds if you ever need surgery or a procedure. The good news is that NovoSeven® RT prevents bleeds during and after surgery and procedures in people with GT.

Talk to your doctor for more information on the surgical use of NovoSeven® RT.

What about surgery and procedures?

Approved for surgical use and procedures for patients with GT with refractoriness to platelets.

Get information on surgery

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Meet Kali. NovoSeven® RT fits in when she's on the go.

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Icon: 5-step purification process of NovoSeven® RT (Coagulation Factor VIIa [Recombinant])

Recombinant manufacturing

minimizes risk of viral contamination.

Learn about proven safety

Selected Important Safety Information

What is the most important information I should know about NovoSeven® RT?

NovoSeven® RT may cause serious side effects, including:

  • Serious blood clots that form in veins and arteries with the use of NovoSeven® RT have been reported
  • Your healthcare provider should discuss the risks and explain the signs and symptoms of blood clots to you. Some signs of a blood clot may include pain, swelling, warmth, redness, or a lump in your legs or arms, chest pain, shortness of breath, or sudden severe headache and/or loss of consciousness or function
  • Your healthcare provider should monitor you for blood clots during treatment with NovoSeven® RT

What is NovoSeven® RT?

NovoSeven® RT (coagulation Factor VIIa, recombinant) is an injectable medicine used for:

  • Treatment of bleeding and prevention of bleeding for surgeries and procedures in adults and children with hemophilia A or B with inhibitors, congenital Factor VII (FVII) deficiency, and Glanzmann’s thrombasthenia with a decreased or absent response to platelet transfusions
  • Treatment of bleeding and prevention of bleeding for surgeries and procedures in adults with acquired hemophilia

Important Safety Information

What is the most important information I should know about NovoSeven® RT?

NovoSeven® RT may cause serious side effects, including:

  • Serious blood clots that form in veins and arteries with the use of NovoSeven® RT have been reported
  • Your healthcare provider should discuss the risks and explain the signs and symptoms of blood clots to you. Some signs of a blood clot may include pain, swelling, warmth, redness, or a lump in your legs or arms, chest pain, shortness of breath, or sudden severe headache and/or loss of consciousness or function
  • Your healthcare provider should monitor you for blood clots during treatment with NovoSeven® RT
  • You should not use NovoSeven® RT if you have ever had allergic (hypersensitivity) reactions, including severe, whole body reactions (anaphylaxis) to NovoSeven® RT, any of its ingredients, or mice, hamsters, or cows. Signs of allergic reaction include shortness of breath, rash, itching (pruritus), redness of the skin (erythema), or fainting/dizziness

What should I tell my healthcare provider before using NovoSeven® RT?

  • Tell your healthcare provider if you have any of the following, as these may increase your risk of blood clots:
    • congenital hemophilia and are also receiving treatment with aPCCs (activated prothrombin complex concentrates)
    • are an older patient particularly with acquired hemophilia and receiving other agents to stop bleeding
    • history of heart or blood vessel diseases
  • Tell your healthcare provider and pharmacist about all the medicines you take, including all prescription and non-prescription medicines, such as over-the-counter medicines, supplements, or herbal remedies

What are the possible side effects of NovoSeven® RT?

  • The most common and serious side effects are blood clots
  • Tell your healthcare provider about any side effects that bother you or do not go away, and seek medical help right away if you have signs of a blood clot or allergic reaction

Please click here for Prescribing Information